Progenicare is now a part of Isto Biologics



  • What is it?

    The OrthoPAT is an orthopedic perioperative autotransfusion system that collects blood loss both intraoperatively, as well as postoperatively, and the blood is then filtered, washed, concentrated and re-infused back into the patient. Providing the patient with improved red blood cell concentration, lower dependency upon allogeneic blood, and reduction in overall cell contaminates - reducing the risk of infection and lessening patient recovery time while reducing surgical costs. OrthoPAT red blood cell concentrations typically range between 70-80%.
  • Who is it for?

    OrthoPat is used primarily during orthopedic surgery when the surgeon expects a moderate amount of intraopertive or post-operative blood loss. The OrtoPat can process salvaged blood from the surgical site a rate that is less than or equal to 2 liters per hour. OrthoPAT is indicated for patients who meet at least one of the following criteria: - The patient is expected to lose sufficient blood in the perioperative period so as to require RBC transfusion, and autotransfusion will likely reduce or eliminate the need for allogeneic blood transfusion. - Religious beliefs cause the patient to refuse allogeneic transfusion, but accept autologous transfusion. - Compatible allogeneic blood is not available. - The patient is unable to donate sufficient quantities of autologous blood prior to surgery to adequately cover the anticipated transfusion requirement. - The patient or physician prefers perioperative autotransfusion rather than preoperative autologous donation or transfusion of allogeneic blood.
  • How does it work?

    The OrthoPAT process is broken into collection, filtering, washing, and re-infusion phases. Collection of red blood cells from the operative field is collected through the use of a dedicated double-lumen suction device. One lumen suctions blood from the operative field and the other lumen adds a predetermined volume of heparinized saline to the salvaged blood. The anti-coagulated blood is then passed through a filter and collected into a collection reservoir. Separation of the components is achieved through the use of a precision centrifuge. The red blood cells are then washed and filtered through a semi-permeable membrane, which removes free haemoglobin, plasma, platelets, white blood cells, and heparin. The salvaged red blood cells are then re-suspended in normal saline with a resultant haematocrit of 50–80%. The salvaged cells may subsequently be transfused back into the patient anytime with a six hour window. The OrthoPAT device follows the patient throughout the intraoperative and postoperative settings, ensuring postoperative blood loss is minimized.